Characteristic | Details |
---|---|
Active Ingredient | Sildenafil Citrate |
Dosage Forms | 50 mg, 100 mg tablets |
Indications | Erectile Dysfunction (ED) |
Route of Administration | Oral |
Onset of Action | 30-60 minutes |
Duration | 4-6 hours |
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Pharmacokinetics
Sildenafil 100 mg, the active component in Aurogra, functions by inhibiting the enzyme PDE5. This leads to increased blood flow in the corpus cavernosum. Absorption occurs rapidly, with peak plasma concentrations reached within 30 to 120 minutes. The presence of a high-fat meal can delay the absorption. The substance exhibits a volume of distribution of approximately 105 L.
Metabolism takes place primarily in the liver, mediated by CYP3A4 and CYP2C9. Its main metabolite, N-desmethylsildenafil, possesses similar properties but reduced potency. Excretion involves renal and fecal pathways. The average terminal half-life is around 4 hours.
Dosage Information
Aurogra 100 mg tablets are designed for oral intake. The recommended starting dose is 50 mg, adjustable based on efficacy and tolerance. Increments should not exceed 100 mg. Maximum dosing frequency is once per day.
Individual response can vary; hence adjustments are sometimes necessary. Patients with hepatic impairment or renal dysfunction may require dose modifications. Consult with healthcare professionals for tailored guidance.
Indications
Aurogra primarily targets erectile dysfunction (ED), a condition characterized by the inability to achieve or maintain an erection sufficient for satisfactory sexual performance. By enhancing erectile response when a man is sexually stimulated, the drug aids in successful intercourse.
This condition often stems from physical or psychological factors. Sildenafil in Aurogra addresses physiological barriers by improving hemodynamic processes.
Aurogra Interactions
The interaction potential of Aurogra 50 mg necessitates careful consideration. Concomitant use with nitrates or nitric oxide donors is contraindicated due to the risk of significant hypotension.
Other interactions include those with alpha-blockers, antihypertensives, and CYP3A4 inhibitors. Grapefruit juice can affect drug metabolism. Patients should disclose all medications they are taking to their healthcare provider to prevent adverse interactions.
Aurogra Side effects
Adverse reactions to Aurogra can vary. Common side effects include headaches, flushing, and nasal congestion. More severe reactions, though rare, comprise sudden hearing loss, visual disturbances, or priapism.
Patients experiencing significant side effects should seek immediate medical attention. Continued monitoring for any unexpected reactions during therapy is vital for ensuring safety.
Aurogra Over The Counter
Aurogra is not available as an over-the-counter medication. It requires a prescription from a licensed healthcare professional. This ensures that the drug is appropriate for the patient’s specific condition and reduces the risk of contraindications.
Pharmacies must adhere to regulations that prohibit unsupervised sale. Patients should be wary of unauthorized sellers to avoid counterfeit products.
Additional Safety Tips
- Consult a physician before starting treatment.
- Follow prescribed dosage instructions precisely.
- Do not mix with alcohol or recreational drugs.
- Report any unusual side effects to a healthcare provider.
Aurogra stands as a reliable choice for addressing erectile dysfunction. Its pharmacokinetic profile and interaction potential highlight the importance of medical guidance. As a prescription medication, it ensures regulated and safe usage.